The settings for ANY plugin can be
Global - the settings for the plugin apply to ALL profiles
Specific - the settings for the plugin apply to the selected profile only
Off - the settings are not required for the selected profile
The required option is set using the Slider at the foot of each plugin, as shown below
It can be left at Global (meaning the plugin settings apply to all profiles)
Or clicked to set to Specific, which then shows the Profile selector list
and then the on/off option changed as required
The required settings can then be configured as required.